연구실소개

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HOME 연구실소개 미세유체공학및나노바이오시스템실험실

미세유체공학및나노바이오시스템실험실

실험실 소개

국립금오공과대학교 미세유체공학 및 나노바이오시스템 실험실은 마이크로/나노미터 스케일의 초정밀 형상 제작기술과 이러한 미세유체에서 발생하는 특이적인 유동 및 물질전달 현상에 대한 기초지식을 바탕으로, 바이오분석 및 바이오공정 자동화 (Lab on a Chip), 체외진단 및 병원성인자 검출 (Invitro Diagnosis & Biosensing), 환경 오염/독성인자 분석 및 처리 (Pollutant management) 등 인류의 건강한 삶을 추구하는 기계-바이오 융복합 공학기술 및 바이오 응용 시스템을 개발합니다. 특히 미세유체 기반 나노-바이오 센서 플랫폼은 적은 시료 용량으로 보다 신속하고 정밀하게 여러 항목에 대한 병렬적 다중 분석이 가능하여, 4차 산업혁명 시대의 사물인터넷, 빅데이터, 인공지능 기술의 발전과 맞물려 개인맞춤형 정밀의료 시대를 촉진시킬 것이라 기대합니다.

주요 연구 분야
국립금오공과대학교 기계시스템공학부 미세유체공학 및 나노바이오시스템 실험실의 연구분야
Multiscale Nano-Bio mechatronics
Micro
001. Multiscale Micor Fabrication
Unconventional micro-nano Fab (e.q., crack, wrinkle)
Membranes
3D Printer
Nano
002. Nanomechanical Fundamentals
Transport phenomena
Electrokinetics
Ultrafiltration
Nanofluidic phenomena
Bio
003. Biosensing Platforms
In-vitro diagnosis (IVD)
Biosample preparation
Wearable biosensors
On-site bio-environmental detection device
Mech.
004. Automated Bio-processes
Bio-system optimization & automation
Fully-integrated biomedical analysis system
Mechatronics
  • [Microfluidics] Micro/Nanofluidic Engineering for Biosample Preparation & Analysis
  • [Bio-MEMS] On-site Biomedical / Environmental Sensing Platfroms
  • [Mechatronics] Automation of Conventional Biosystems & Bioprocessing
  • [Nanotechnology] Unconventional Nanofabrication & Nanoengineering

교수님 소개

김민석
  • 프로필
  • 학력 및 경력
    • 2004-2010: 전남대학교 공학사
    • 2010-2015: 울산과학기술원(UNIST), 공학박사
    • 2015-2015: 울산과학기술원(UNIST), 박사후연구원
    • 2015-2017: Massachusetts Institute of Technology(MIT), 박사후연구원
    • 2017-2019: 한국기계연구원(KIMM), 선임연구원
    • 2019-현재: 국립금오공과대학교 기계시스템공학부, 조교수

    • 주요 논문

    • Jan 2018 M. Kim, L. Wu, B. Kim, D. T. Hung, and J. Han*, “Continuous and High-Throughput Electromechanical Lysis of Bacterial Pathogens Using Ion Concentration Polarization”, Analytical Chemistry, 2018 Jan 2;90(1):872-880 (IF 6.320, Top 5%)
    • Sep 2017 M. Kim J. Bae, and T. Kim*, “Long-term and Programmable Bacterial Subculture in Completely Automated Microchemostats”, Analytical Chemistry, 2017 Sep 19;89(18):9676-9684 (IF 6.320, Top 5%).
    • Oct 2017 M. Kim, J.-W. Lim, S.-K. Lee*, and T. Kim*, “Nanoscale Hydrodynamic Film for Diffusive Mass Transport Control in Compartmentalized Microfluidic Chambers”, Analytical Chemistry, 2017 Oct 3;89(19):10286-10295 (IF 6.320, Top 5%). This paper was selected as the front cover of the issue.
    • Aug 2016 B. Kim, R. Kwak, H. Kwon, S. V. Pham, M. Kim, B. Al-anzi, G. Lim, and J. Han*, “Purification of high salinity brine by multi-stage ion concentration polarization desalination”, Scientific Reports, 2016 Aug 22;6:31850 (IF 5.228)
    • Mar 2016 J. Lee, M. Kim, J.-Y Park, and T. Kim*, “Self-assembled particle membranes for in-situ concentration and chemostat-like cultivation of microorganisms on a chip”, Lab on a Chip, 2016 Mar 21;16(6):1072-80. (IF 5.586, Top 10%)
    • May 2016 M. Kim, D. Kim, D. Ha and T. Kim*, “Cracking-assisted fabrication of nanoscale patterns for micro-/nanotechnological applications”, Nanoscale, 2016 May 5;8(18):9461-79. (IF 7.760, Top 10%) This paper was selected as the inside front cover of the issue.
    • Nov 2015 M. Kim and T. Kim*, “Crack-photolithography for membrane-free diffusion-based micro/nanofluidic devices”, Analytical Chemistry, 2015 Nov 17;87(22):11215-23. (IF 5.886, Top 5%) This paper was selected as the front cover of the issue.
    • Mar 2015 M. Kim†, J.-W. Lim†, H.-J. Kim, S.-K. Lee, S.-J. Lee*, and T. Kim*, “Chemostat-like microfluidic platform for highly sensitive detection of heavy metal ions using microbial biosensors”, Biosensors and Bioelectronics, 2015 Mar 15;65:257-64. (IF 7.476, Top 5%).
    • Fab 2015 M. Kim, D. Ha, and T. Kim*, “Cracking-assisted photolithography for mixed-scale patterning and nanofluidic applications”, Nature Communications, 2015 Feb 18;6:6247. (IF 13.092, Top 5%) This paper was highlighted in many news media.
    • Jun 2014 M. Kim and T. Kim*, “Aptamer-functionalized microtubules for continuous and selective concentration of target analytes”, Sensors and Actuators B: Chemical, 2014 Jun 07; 202:1229-36. (IF 4.758, Top 5%)
    • Jan 2014 Y.-K. Nam, M. Kim, and T. Kim*, “Pneumatically controlled multi-level microchannel for separation and extraction of microparticles”, Sensor Actuat B-Chem, 2014 Jan 07;190:86-92. (IF 4.758, Top 5%)
    • Oct 2013 M. Kim and T. Kim*, “Integration of nanoporous membranes into microfluidic devices: electrokinetic bio-sample pre-concentration”, Analyst, 2013 Oct 21;138(20):6007-15. (IF 4.033, Top 10%)
    • Sep 2013 M. Kim, Jia, M, Kim, Y., and T. Kim*, “Rapid and accurate generation of various concentration gradients using polydimethylsiloxane-sealed hydrogel device”, Microfluidics and Nanofluidics, 2013 Sep 20;16:645-654. (IF 2.537, Top 10%)
    • Sep 2013 Y.-K. Nam, M. Kim, and T. Kim*, “Fabricating a multi-level barrier-integrated microfluidic device using grey-scale photolithography”, Journal of Micromechanics and Microengineering, 2013 Sep 12;23:105015. (IF 1.725, Q2)
    • Mar 2013 M. Kim, M. Jia, and T. Kim*, “Ion concentration polarization in a single and open microchannel induced by a surface-patterned perm-selective film”, Analyst, 2013 Mar 7;138(5):1370-8. (IF 4.033, Top 10%) This paper was selected as the inside front cover of the issue.
    • Jan 2012 W.-S. Choi, M. Kim, S. Park, S.-K. Lee and T. Kim*, “Patterning and transferring hydrogel-encapsulated bacterial cells for quantitative analysis of synthetically engineered genetic circuits”, Biomaterials, 2012 Jan;33(2):624-33. (IF 8.387, Top 5%)
    • Jun 2011 P. Vinuselvi, S. Park, M. Kim, J.-M. Park, T. Kim*, and S.-K. Lee*, “Microfluidic technologies for synthetic biology”, International Journal of Molecular Sciences, 2011 Jun 03;12:35-3593 (IF 3.257, Q1)
    • Aug 2011 M. Kim, S.-H. Kim S.-K. Lee*, and T. Kim*, “Microfluidic device for analyzing preferential chemotaxis and chemoreceptor sensitivity of bacterial cells toward carbon sources”, Analyst, 2011 Aug 21;136(16):3238-43. (IF 4.033, Top 10%) This paper was selected as the front cover of the issue.
    • Nov 2010 M. Kim and T. Kim*, “Diffusion-based and long-range concentration gradients of multi-chemicals for bacterial chemotaxis assays, Analytical Chemistry, 2010 Nov 15;82(22):9401-9. (IF 5.825, Top 5%) This paper was highlighted as a news article in the American Chemical Society (ACS C&EN).